We develop statistical methods to characterize the genetic architecture of common disease. We are a part of the Harvard Medical School Department of Biomedical Informatics, and we are affiliated with the Broad Institute Program in Medical and Population Genetics.
You can read about our research, see our current and former lab members, and see a list of publications.
For prospective doctoral students, please click here.
News
Nov 2026
- Wenhan Lu’s paper, Effect heterogeneity reveals complex pleiotropic effects of rare coding variants, was published in The American Journal of Human Genetics. Congratulations, Wenhan!
- Luke O’Connor’s paper, Self-Programmed Execution for Language-Model Agents, was accepted at NeurIPS 2026.
Oct 2026
- Qiuqi (Autumn) Xu has joined the lab as a master's student. Welcome, Autumn!
- Kangcheng Hou’s manuscript, Functional architecture of rare protein coding variation across 786,871 exomes, was posted on medRxiv. Congratulations, Kangcheng!
Aug 2026
- Ajay Nadig's manuscript, Estimating the contribution of coding mutations to autism, was posted on medRxiv. Congratulations, Ajay!
- Pouria Salehi Nowbandegani's paper, Defining and cataloging variants in pangenome graphs, was published in Cell Genomics. Congratulations, Pouria!